Platelet-Mediated Modulation of Adaptive Immunity
نویسندگان
چکیده
منابع مشابه
Platelet-mediated modulation of adaptive immunity: unique delivery of CD154 signal by platelet-derived membrane vesicles.
Although mounting evidence indicates that platelets participate in the modulation of both innate and adaptive immunity, the mechanisms by which platelets exert these effects have not been clearly defined. The study reported herein uses a previously documented adoptive transfer model to investigate the ability of platelet-derived membrane vesicles to communicate activation signals to the B-cell ...
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Short Title: PDMV deliver CD154 signals to B cells Daniel L. Sprague, Bennett D. Elzey, Scott A. Crist, Thomas J. Waldschmidt, Robert J. Jensen, and Timothy L. Ratliff Department of Urology, University of Iowa Medical Scientist Training Program, University of Iowa Department of Microbiology, University of Iowa Department of Pathology, University of Iowa Interdisciplinary Immunology Program, Uni...
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Aberrant immune responses represent the underlying cause of central nervous system (CNS) autoimmunity, including multiple sclerosis (MS). Recent evidence implicated the crosstalk between coagulation and immunity in CNS autoimmunity. Here we identify coagulation factor XII (FXII), the initiator of the intrinsic coagulation cascade and the kallikrein-kinin system, as a specific immune cell modula...
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Cathelicidins are a family of host defence peptides that are known to selectively alter innate immunity in response to infection and other changes in immune status. A study in this issue of the European Journal of Immunology elucidates a new role for mouse cathelin-related antimicrobial peptide in the adaptive immune response by clearly demonstrating for the first time that a cathelicidin can a...
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ژورنال
عنوان ژورنال: Immunity
سال: 2003
ISSN: 1074-7613
DOI: 10.1016/s1074-7613(03)00177-8